منابع مشابه
Epigenetics of prostate cancer: beyond DNA methylation
Epigenetic mechanisms permit the stable inheritance of cellular properties without changes in DNA sequence or amount. In prostate carcinoma, epigenetic mechanisms are essential for development and progression, complementing, amplifying and diversifying genetic alterations. DNA hypermethylation affects at least 30 individual genes, while repetitive sequences including retrotransposons and select...
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Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...
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ژورنال
عنوان ژورنال: Toxicology Mechanisms and Methods
سال: 2011
ISSN: 1537-6516,1537-6524
DOI: 10.3109/15376516.2011.562671